This awesome project comes from the nV-level measurement instrument challenge launched by xDevs. The project requirements are relatively difficult and only one author has completed it. The author has open sourced all project materials and provided detailed explanations (in English).
The BioAmp EXG Pill is a powerful small analog front end (AFE) biopotential signal acquisition board that pairs with any microcontroller unit (MCU) or single board computer (SBC) with an analog-to-digital converter (ADC)) Such as Arduino UNO & Nano, Espressif ESP32, Adafruit QtPy, STM32 Blue Pill, BeagleBone Black and Raspberry Pi Pico, just to name a few. It also works with any dedicated ADC such as Texas Instruments ADS1115 and ADS131M0x etc.
High-precision digital-to-analog conversion using AD5542/AD5541 16-bit voltage output DACs, ADR421 voltage reference, and AD8628 auto-zero op amp
4-channel, flexible, configurable, voltage and current output circuit for I/O card and PLC applications
16-bit, single-supply, buffered voltage output analog-to-digital converter with less than ±1 LSB integral and differential nonlinearity