Dynamic myocardial stress CT perfusion imaging challenges cardiac MRI

A preliminary study led by Markus Weininger of the University of South Carolina Charleston School of Medicine found that cardiac MRI may face challenges in adenosine stress-induced myocardial perfusion CT imaging. The study won the RSNA Research Achievement Award, and the team will discuss dual-source CT technology at RSNA.

The research team used dual-source CT imaging, prospective coronary CT angiography, dynamic adenosine stress in a single myocardial perfusion imaging scanner "shuttle" mode, and delayed enhancement imaging in 20 patients. As with CT, all subjects underwent stress/rest delayed enhancement MRI.

The researchers assessed the extent of myocardial perfusion defect and compared the myocardial-to-left ventricular upslope index obtained by CT and MRI.

The study found that the sensitivity of MRI and CT for detecting myocardial perfusion defects was 86% and 98%, respectively, and the positive and negative predictive values ​​were 93% and 94%, respectively.

The team ultimately concluded that adenosine stress one-time myocardial perfusion imaging CT can obtain qualitative and semi-quantitative parameters in myocardial blood perfusion, which is similar to the effect of MRI, and can also obtain the absolute value of myocardial blood flow.