The first national standard in the field of organ chips in my country, GB/T44831-2024 "General Technical Requirements for Skin Chips", led by Professor Gu Zhongze's team from the Suzhou Institute of Medical Devices of Southeast University, was officially released. The first national standard for organ chips in my country released this time was drafted by the team of Dean Gu Zhongze and completed by 21 units including Southeast University, Biobio Group Co., Ltd., Jiangsu Avid Biotechnology Co., Ltd., Tsinghua University, Southern Medical University, Nanjing Food and Drug Administration, Nanjing Metrology Supervision and Inspection Institute.
This standard mainly stipulates the relevant term definitions of skin chips, the appearance of skin chips, cell sources, component performance, and technical requirements for biological performance. It is applicable to the design, production and testing of skin chip products using microfluidic chips as carriers.
It is reported that skin chip, as an important branch of human organ chip, uses advanced microfluidic technology to successfully simulate the biochemical and physiological characteristics of the skin and construct a micro cell and tissue culture platform with barrier structure and function.
Its unique high-throughput, automated culture and detection capabilities indicate that it will become an innovative tool in the fields of toxicology testing, drug screening, and cosmetics evaluation. It is expected to gradually replace traditional two-dimensional cell culture, animal experiments, and even artificial skin experiments, leading skin-related in vitro evaluation technology to new heights.
Looking into the future, with the continuous iteration and innovation of technology, we may see more types of organ chips, such as heart chips, liver chips, etc., which will continue to emerge. They will play an important role in personalized medicine, precision treatment and other aspects.
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