The first COVID-19 DNA vaccine begins human trials, Gates Foundation funds Inovio's research and development, and it will be available in 18 months at the earliest

Jia Haonan from Aofei Temple
Quantum Bit Report | Public Account QbitAI

In the face of the new coronavirus epidemic, Gates took action again.

On April 6, a new coronavirus vaccine funded by the Gates Foundation passed FDA approval and is about to begin human trials.

This is the second COVID-19 vaccine approved for human trials in the United States, and it is also the world's first DNA vaccine to be tested on humans .

The basic principle of DNA vaccines is to directly inject a DNA vector plasmid that has been edited to express antigenic proteins into the target organism, allowing it to produce antigens directly in the organism and stimulate the immune system to produce antibodies.

这种新疫苗由Inovio公司研发。目前的动物实验取得了非常好的效果。实验动物注射疫苗后产生了显著的免疫反应。

You may be surprised at the speed of vaccine development. In fact, this is not the first time that the company has developed a DNA vaccine. Earlier DNA vaccine research and development for Middle East Respiratory Syndrome has been quite effective. In the Phase 1 human trial, the number of target antibodies produced and the duration of immune response were both excellent.

This gives researchers the technical reserves and confidence to quickly develop a new coronavirus vaccine. Of course, the support of the Gates Foundation and other non-profit organizations is also key to quickly conducting human trials.

Inovio has scaled up its production to produce thousands of doses of the vaccine in just a few weeks, enough for Phase 1 and 2 human trials.

The human trial of the new coronavirus vaccine will be conducted on 40 healthy adults, and the specific participants will be screened under the guidance of the University of Pennsylvania School of Medicine and the Kansas Center for Drug Research.

If the results of human trials show that the vaccine is both effective and safe, its clinical value may be recognized this summer.

Inovio also said that it will be able to produce 1 million doses of the vaccine by the end of this year for large-scale clinical trials. It can also be used to respond to emergencies after obtaining relevant authorization.

Although it will take 18 months for the vaccine to be officially approved for marketing , the rapid pace of development has given the world hope amid anxiety and panic that an effective vaccine will be available as scheduled.

Recently, conspiracy theories about Gates have been circulating on foreign social media. Many netizens are convinced that the new coronavirus was developed by Gates, who intended to screen outstanding humans and attempt to make a profit through vaccines.

The outcry against Gates has intensified, with many celebrities joining in. Some extremists have even issued death threats against Gates.

It has to be said that the stupidity and blindness shown by humans in the crisis are laughable and helpless. Gates is really saving all mankind under the "threat of death".

The Gates Foundation has spent billions of dollars to fight the COVID-19 pandemic, investing in the development of multiple vaccines.

On April 6, in an interview with well-known talk show host "Cui Wa", Gates said that perhaps only two of the vaccines he invested in would be able to be marketed in the end, but it is worth spending the money because we are racing against time.

Even if most of the money is wasted, the billions of dollars are still worth spending compared to the trillions of dollars in economic losses.

Facing the slander, Gates did not respond in public.

References:

https://techcrunch.com/2020/04/06/a-second-potential-covid-19-vaccine-backed-by-bill-and-melinda-gates-is-entering-human-testing/

http://ir.inovio.com/news-and-media/news/press-release-details/2020/INOVIO-Initiates-Phase-1-Clinical-Trial-Of-Its-COVID-19-Vaccine-and-Plans-First-Dose-Today/default.aspx