In vitro chemistry analyzer performance is poor? This solution can help you

Life science and medical instrumentation includes a variety of different systems, such as in vitro chemical analyzers, flow cytometers, infusion pumps, dialysis equipment, ventilators, catheters and other equipment. In vitro chemical analyzers use a number of electrochemical and optical techniques to analyze blood, urine, cerebrospinal fluid and other biological samples. The most widely used technology is optical measurement, examples include colorimetric, absorption, spectrometric and fluorescence detection methods. These methods can be used to measure chemicals such as antigens, molecules and proteins in body fluids. These technologies are widely used in hospitals, clinics and service agencies such as epidemic prevention stations because they can achieve fast measurement functions, high sensitivity and high accuracy even for small doses of chemicals.

An in vitro chemistry analyzer is a very complex system that includes an optical engine (composed of a light source, detectors, and other optical components ) , sample movement/fluidics, automated control and processing, power management, and environmental monitoring and control (temperature, pressure, humidity ) . To increase efficiency, biochemical analyzers have become highly automated. The technology automates sample loading, tube cleaning, mechanical control, and data processing. The operator simply inserts the sample to be analyzed, selects the program, and starts the instrument.

In vitro chemistry analyzers can be classified by processing capacity into large (processing more than 600 samples per hour), medium (300-600 samples per hour) and small (less than 300 samples per hour). They have different characteristics and can be classified as laboratory testers or point-of-care testers (POCT, deployed next to the patient to speed up test turnaround time).

• Measurement speed is important

• Reagent volume control is important to reduce costs and ensure consistency

• Optical system control and precision are key elements of the system

Spectrophotometer

• I/V converters in photodiode inputs require low bias current, high input impedance, low noise, low offset op amps

• Fast, high-precision, simultaneous sampling ADC

• Low noise and stable power supply

• Low noise and stable light source

Temperature control is extremely important for reagents and chemical reactions

• Enzymes are sensitive to temperature fluctuations

• The reaction rate is very sensitive to temperature

• The general temperature range is body temperature, with a maximum accuracy of ±0.1°C

• Sometimes integrated heating/cooling equipment for smooth temperature control

Automatic control is necessary to improve execution efficiency

• Precise step and position control

• Multi-axis motor motion control for moving and transferring samples within the instrument

• Accurate level measurement

• Pressure testing for detecting blockage

• Precise and fast sample loading and cleaning

Data processing and classification

• High-speed processor for multi-channel data processing

• DSP to accelerate complex analysis

• Provide inspection reports as quickly as possible

ADI provides a wide range of amplifiers for I/V conversion, filter design, signal conditioning and ADC driving, and provides data conversion, signal processing and power management solutions to optimize product quality and reliability for biochemical analyzer applications.

In addition, ADI provides evaluation boards, simulation tools, and application expertise to support customers' design and development efforts.

The figure below shows the main signal chain for an ADI in vitro chemistry analyzer.

The above signal chain represents an in vitro chemistry analyzer system. In a specific design, the technical requirements of the modules may be different, but in the full document of [ADI In Vitro Chemistry Analyzer Solution], representative ADI products that can meet some requirements are listed. Please click "Read the original text" to download and learn more~